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目的评价苯磺酸左旋氨氯地平(施慧达)和左旋氨氯地平(络活喜)对原发性高血压的降压疗效及毒副反应。方法选择确证后的原发性高血压患者80例,其中男53例,女27例,随机分为两组,按2.5～5.0mg/d剂量口服施慧达或络活喜4周,观察治疗前后降压疗效及发生不良反应(心悸、头痛、头晕、面色潮红、下肢浮肿)的例数。结果施慧达组的总有效率为86%,显效率为70%,未发现不良反应;络活喜组的总有效率为83%,显效率为65%,不良反应例数为3例。结论施慧达的降压效果稍高于络活喜,且不易引发不良反应。
Objective To evaluate the antihypertensive effects and side effects of levamlodipine besylate and levamlodipine on essential hypertension. Methods Eighty patients with confirmed essential hypertension were selected, including 53 males and 27 females, who were randomly divided into two groups. The patients were treated with 2.5 ~ 5.0 mg / d orally or orally for 4 weeks, and were observed before and after treatment Pressure response and adverse reactions (palpitations, headache, dizziness, flushing, lower extremity edema) cases. Results The total effective rate was 86% and the effective rate was 70%. The total effective rate was 83%, the effective rate was 65% and the number of adverse reactions was 3. Conclusion The effect of antihypertensive Schneider Slightly higher than Luoxuoxi, and not easy to cause adverse reactions.