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在妊娠期,羊膜穿刺术检查对于胎儿的损伤和流产的危险是很小的,但是,直到目前为止,对曾经作过羊膜穿刺术的妇女出生的儿童未曾作过系统随访研究。本文调查了80例母亲曾作这样检查,第一胎出生的,年龄在4岁8个月到7岁之间的儿童。90%羊膜穿刺术的指征是母亲的年龄(35岁或更大些);母亲在生育小孩的平均年龄为37.4岁(标准差4.4)。1例母亲生育的小孩患Down 氏综合征,其余7例有心理学性质的特征。所有儿童(男47,女33)在研究时都做了全面的医学检查,包括神经精神学的估价。他们的病史是在检查时间问母亲。用特殊设计的调查表,也从病历记录中收集资料。没有发现染色体有异常征象。一个女孩位于靠脐上方皮肤有一个小的(直径5毫米)环状的失色素
In pregnancy, amniocentesis is insignificant for the risk of fetal injury and miscarriage, but until now no systematic follow-up study has been conducted on women born to women who had been treated for amniocentesis. This article surveyed 80 mothers who had this examination, the first child was born, aged 4 years 8 months to 7 years old children. Ninety percent of amniocentesis is indicated by the age of the mother (35 or older); the average age of mothers with childbirths is 37.4 years (SD 4.4). One child born to the mother had Down’s syndrome and the remaining seven had psychologic features. All children (male 47, female 33) underwent a comprehensive medical examination at the time of the study, including neuropsychology. Their medical history is to ask their mother at check-up time. Using specially designed questionnaires, data are also collected from medical records. No chromosomal abnormal sign was found. A girl is located on the skin above the umbilicus with a small (5 mm in diameter) annular loss of pigment