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对流行性出血热患者尸检肝脏及肾脏各2例，进行了组织病理与免疫病理研究。流行性出血热患者肝脏细胞有超微结构损伤，在肝细胞及肝窦内皮细胞中可检出特异性病毒抗原，并可见IgG、IgM沉积的免疫荧光。肾组织中肾小管损伤明显，肾小球也有不同程度病变，在肾小球毛细血管内皮细胞，肾小管上皮细胞基底膜及肾间质内可检出病毒抗原及IgG、IgM、C3。上述结果表明特异性免疫复合物在流行性出血热患者肝、肾损害中起到重要作用，但是病毒的直接作用也不可忽视。
Two cases of autopsy liver and kidney were collected from patients with epidemic hemorrhagic fever, and histopathological and immunopathological studies were performed. Liver cells in patients with epidemic hemorrhagic fever have ultrastructural damage, specific virus antigens can be detected in liver cells and sinusoid endothelial cells, and immunofluorescence of IgG and IgM deposition can be seen. Tubular injury in renal tissue is obvious, there are varying degrees of glomerular lesions in the glomerular capillary endothelial cells, tubulointerstitial and renal interstitium can be detected within the viral antigen and IgG, IgM, C3. The above results show that specific immune complexes play an important role in the liver and kidney damage in patients with epidemic hemorrhagic fever, but the direct effect of the virus can not be ignored.