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中医学家们总是试图通过更复杂的药物搭配制造出安全有效的成方成药。而作为天然药物的发展方向之一是,寻找到药物的根本有效成分,然后制造出单分子的药物。目前通过纳米技术试图改变分子微结构的努力,也成为新药开发的一个方向。这些新发展方向与数千年来的中医学家的努力方向相反。这两个新方向开发给中药的毒性带来了改变。对这种中药制造工艺改变造成的毒性变化进行有效科普,将有利于中药资源的开发和利用。
Chinese medical scientists are always trying to make safe and effective prescription drugs through more complex medicines. As one of the development directions of the natural medicine, it is to find the essential active ingredients of the medicine and then make the single-molecule medicine. The current efforts to change the molecular microstructure through nanotechnology have also become a new direction for the development of new drugs. These new directions of development are contrary to the efforts of Chinese medicine practitioners for thousands of years. These two new directions have changed the toxicity of Chinese medicine. An effective science popularization on the change of toxicity caused by the change of the manufacturing process of Chinese traditional medicine will be beneficial to the development and utilization of traditional Chinese medicine resources.