胃粘膜损伤是临床上一种常见的病理表现。以消化性溃疡为例,其人群发生率大约10%。引起损伤的机制迄今仍不清楚。近年来这方面研究的新进展包括:①发现了各种不同结构的受体;②证实前列腺素(prostaglandin,PG)、副交感神经阻滞药、甲氰咪胍等具有细胞保护作用:③对胃粘膜屏障的存在和作用重新作了评价;④把生物化学的方法引入胃肠学的研究,其中胃粘膜损伤过程中细胞能量代谢 Gastric mucosal injury is a common clinical pathology. Take peptic ulcer for example, its population incidence is about 10%. The mechanism causing damage remains unclear so far. In recent years, new research in this area include: ① the discovery of a variety of different receptors; ② prostaglandin (PG), parasympathetic blocker, cimetidine and other cytoprotective effects: ③ on the stomach Mucosal barrier re-evaluation of the existence and role; ④ the introduction of biochemical methods gastrointestinal studies, including gastric mucosal damage in the process of cell energy metabolism