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目的观察甲氨蝶呤(MTX)联合米非司酮或中药治疗输卵管妊娠的疗效。方法 A组口服米非司酮联合MTX单次肌内注射;B组MTX单次肌内注射联合口服中药;C组MTX(50 mg/m2)单次肌内注射。定期监测血人绒毛膜促性腺激素(β-hCG)水平及阴道B超监测包块情况直至正常。结果治愈率A组84.0%、B组84.4%,C组76.0%,A、B两组较C组明显缩短血β-hCG降至正常所需的时间,减少住院日(P<0.01),A、B两组间没有明显的差异(P>0.05),但B组副反应明显比A组少(P<0.05)。结论 MTX单次肌内注射联合中药治疗输卵管妊娠疗效好、副反应少,值得临床推广。
Objective To observe the efficacy of methotrexate (MTX) combined with mifepristone or traditional Chinese medicine in the treatment of tubal pregnancy. Methods Group A was given mifepristone combined with MTX intramuscularly intraperitoneally. Group B received a single intramuscular injection of MTX combined with oral administration of traditional Chinese medicine. Group C received a single intramuscular injection of MTX (50 mg / m2). Regular monitoring of human chorionic gonadotropin (β-hCG) levels and vaginal B-monitoring mass until normal. Results The cure rate was 84.0% in group A, 84.4% in group B, and 76.0% in group C. The time required for the reduction of blood β-hCG to normal in group A and group B was significantly shorter than that in group C, and the length of stay (P <0.01), A There was no significant difference between the two groups (P> 0.05), but the side effects in group B were significantly less than those in group A (P <0.05). Conclusion MTX single intramuscular injection of traditional Chinese medicine treatment of tubal pregnancy with good efficacy, fewer side effects, it is worth clinical promotion.