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目的探讨血清白蛋白(ALB)及非结合胆红素(UCB)检测在新生儿黄疸中的临床应用价值。方法选取新生儿黄疸患者87例,对患儿血清ALB、UCB及血清总胆红素(TSB)含量进行测定。结果对比可知重度黄疸患儿ALB显著低于中度黄疸患儿,TSB及UCB显著高于中度黄疸患儿(P<0.05)。除梗阻性黄疸患儿与其他原因黄疸患儿ALB差异无统计学意义(P>0.05)外,梗阻性黄疸、溶血性黄疸、感染性黄疸及其他原因黄疸患儿其他各指标间差异均有统计学意义(P<0.05)。结论血清ALB及UCB检测在新生儿黄疸诊断中有较高临床应用价值,可用于对患儿病情严重程度进行评估,为治疗方案的确定及预后评价提供有力依据。
Objective To investigate the clinical value of detecting serum albumin (ALB) and unconjugated bilirubin (UCB) in neonatal jaundice. Methods Eighty-seven neonates with jaundice were selected for determination of serum ALB, UCB and serum total bilirubin (TSB) in children. The results show that children with severe jaundice ALB was significantly lower than those with moderate jaundice, TSB and UCB were significantly higher than those of children with moderate jaundice (P <0.05). In addition to the obstructive jaundice in children with other causes of jaundice in ALB was not statistically significant (P> 0.05), obstructive jaundice, hemolytic jaundice, infectious jaundice and other causes of jaundice in children with other indicators were statistically different Significance (P <0.05). Conclusion Serum ALB and UCB detection in the diagnosis of neonatal jaundice has a high clinical value, can be used to assess the severity of the disease in children, to determine the treatment plan and prognosis provide a strong basis.