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目的 探讨细胞角蛋白 2 0 (CK2 0 )在膀胱移行细胞癌 (TCC)中的表达及临床意义。方法 应用免疫组化及图像分析技术检测 5 4例TCC中CK2 0的表达 ,并进行分组比较。结果 CK2 0的表达在有否复发组之间差异有极显著性意义 (P <0 .0 0 1)。结论 CK2 0的表达与TCC生物学行为密切相关 ,为临床预测TCC复发开辟了新方法。
Objective To investigate the expression and clinical significance of cytokeratin 20 (CK20) in bladder transitional cell carcinoma (TCC). Methods Immunohistochemistry and image analysis were used to detect the expression of CK20 in 54 cases of TCC and compared with each other. Results There was a significant difference in the expression of CK20 between the two groups (P <0.01). Conclusion The expression of CK20 is closely related to the biological behavior of TCC, which opens up a new way for predicting the recurrence of TCC clinically.