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人类矮小病毒(Parvovirus,简称HPV)是该属病毒中第一种发现能使人致病的病原体。它对红系祖细胞具有特异性细胞毒作用,能引起溶血性贫血患者的再生障碍危象。本文将描述HPV感染的临床表现、流行病学及实验特征,并复习其他病毒与骨髓衰竭之间的关系,提出研究病毒诱发再障的一些模型及实验途径,也请读者们参考本课题有关的一些早期文献。矮小病毒与骨髓再障一、人类矮小病毒感染与再障危象人们从血清筛选乙型肝炎病毒时,发现了人类矮小病毒。11份血清(献血员及病人)用对流免疫电泳法测定乙型肝炎表面抗原阳性,但使用了较特异的放射免疫法及被动血凝法却出现阴性结果,故怀疑前述的阳性结果可能并
Parvovirus (HPV) is the first virus in the genus that can cause human pathogenicity. It has a specific cytotoxic effect on erythroid progenitor cells, can cause crisis of aplastic disorder in patients with hemolytic anemia. This article will describe the clinical manifestations of HPV infection, epidemiology and experimental characteristics, and review the relationship between other viruses and bone marrow failure, proposed to study virus-induced aplastic anemia and some experimental models, but also readers refer to the subject of Some early literature. Dwarf virus and bone marrow aplastic disorder, human dwarf virus infection and aplastic crisis people from the serum screening of hepatitis B virus, the human short virus was found. Eleven serums (blood donors and patients) were positive for hepatitis B surface antigen by convective immuno-electrophoresis, but more specific radioimmunoassay and passive coagulation showed negative results. Therefore, it is suspected that the aforementioned positive result may be