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粒细胞集落刺激因子(G-CSF)是一种前炎症因子,具有调节粒系祖细胞分化、增殖及增强成熟粒细胞吞噬和杀菌功能的作用,并可促进中性粒细胞向感染灶聚集,对抗感染的非特异性细胞免疫起着重要的作用。为了探讨G-CSF在儿童肺炎中的临床意义,我们检测218例肺炎患儿血清G-CSF水平,现报道如下。
Granulocyte colony stimulating factor (G-CSF) is a proinflammatory cytokine that regulates the differentiation and proliferation of granulocyte-derived progenitor cells and enhances phagocytosis and bactericidal activity of mature granulocytes. It can also promote the aggregation of neutrophils into the focus of infection, Non-specific cellular immunity against infection plays an important role. In order to investigate the clinical significance of G-CSF in children with pneumonia, we detected serum G-CSF levels in 218 children with pneumonia and are reported as follows.