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对充血性心力衰竭已往都是用洋地黄、利尿药及β—受体兴奋剂等药物治疗。近年来,以减轻心脏前、后负荷为治疗目的的血管扩张药在临床上应用以来,糖皮质激素就有些逊色了。本文主要概述糖皮质激素对充血性心力衰竭的作用机制及其效果。一、糖皮质激素的效果ACTH 及天然类固醇的氢化可的松、与其相似的类固醇可的松、泼尼松等尽管都有明显的钠潴留作用,但对难治性心力衰竭有时是有效的。Camara 等报道伴有顽固性浮肿、严重肺郁血、阵发性呼吸困难或重症肺部疾患的心脏病21例,在洋地黄和汞利尿剂合用的同时,20例加用ACTH,1例加用可的松,观
For the past, congestive heart failure is treated with digitalis, diuretics and β-receptor agonists and other drugs. In recent years, in order to reduce the heart before and after the load for the treatment of vasodilators in clinical applications, glucocorticoid somewhat inferior. This article summarizes the mechanism and effect of glucocorticoids on congestive heart failure. First, the effect of glucocorticoids ACTH and natural steroid hydrocortisone, and similar steroids cortisone, prednisone and so on, although there are obvious sodium retention, but sometimes refractory heart failure is effective. Camara et al reported 21 patients with refractory edema, severe pulmonary depression, paroxysmal dyspnea or severe pulmonary disease in 21 cases. In combination with digitalis and mercury diuretics, 20 cases plus ACTH, 1 case plus With cortisone, concept