论文部分内容阅读
1978年Melding等在静脉注射利多卡因有效的启示下应用卡马西平治疗耳鸣获得了进展,随后Emmett和Shea(1980)报告了应用一种作用类似于利多卡因的口服药tocainide盐酸盐治疗耳鸣的鼓舞人心的结果。本试验目的就是对这一疗法及其可能出现的副作用的性质和发生率进行评价。初步试验是在12名患者(5男,7女)中进行的,之后又在26名患者(10男,16女)中进行了随机对照双盲试验。实验过程是:先全面地收集患者的病史,进行体检、中枢神经系统检查、语言和纯音听阈测定等特殊检查和生化方面的检验。每个患者先接受100mg利多卡因静注,
In 1978, Melding et al. Made progress in the application of carbamazepine for the treatment of tinnitus under the effective inspiration of intravenous injection of lidocaine. Subsequently, Emmett and Shea (1980) reported the use of tocainide hydrochloride as an oral medication similar to lidocaine Inspirational result of tinnitus. The purpose of this trial is to evaluate the nature and incidence of this therapy and its possible side effects. The initial trial was performed in 12 patients (5 males and 7 females) followed by a randomized double-blind trial in 26 patients (10 males and 16 females). The experimental process is: first comprehensively collect the patient’s medical history, physical examination, central nervous system examination, language and pure tone hearing threshold and other special inspection and biochemical tests. Each patient received intravenous lidocaine 100mg intravenously,