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目的了解鲍曼不动杆菌感染现状，分析其耐药谱变迁，动态监测其耐药性及其发展趋势，为临床各科室控制感染及合理应用抗菌药物提供依据。方法用VITEK2鉴定系统对菌株进行鉴定及药敏试验。用WHONET5.5软件对药敏结果进行统计学分析。结果分离出鲍曼不动杆菌405株，其检出率以重症监护室、呼吸科的居多，分别为20.5%、10.6%。其次是泌尿外科、神经外科、乳腺烧伤外科及皮肤痔瘘科。2012~2013年所监测抗生素的耐药性有逐步升高的趋势，尤以2013年上升更为显著，特别是鲍曼不动杆菌对碳青霉烯类耐药率增加迅速，重症监护室病房鲍曼不动杆菌对亚胺培南耐药率达80.1%。结论鲍曼不动杆菌耐药性日趋严重，应引起临床科室以及医院感染科室的高度重视。“,”Objective Understanding of acinetobacter baumanni infection status, analyze the changes of drug resistance of dynamic monitoring the drug resistance and developing trend of clinical infection control department and provide evidence for reasonable application of antimicrobial agents.Methods With VITEK2 identification system for identification and drug sensitive test strains.With WHONET5.5 software with the result of drug susceptibility for statistical analysis.Results Isolated 405 strains of acinetobacter baumanni , the detection rate in the majority with intensive care unit, respiratory, 20.5%, 10.6%respectively. Secondly, urology, neurosurgery, breast burn surgery and skin division.2012~2012 monitoring antibiotic resistance has a tendency to escalate, especial y in the rising more dramatical y in 2013, especial y the acinetobacter baumanni on carbon penicil ium alkene antimicrobial increase rapidly, the intensive care unit ward acinetobacter baumanni to imine culture south resistant rate of 80.1.Conclusion Acinetobacter baumanni resistance has become increasingly serious, should cause clinical departments and hospital infection department at aches great importance to.