目的总结九年来我市新生儿疾病筛查的工作经验,对筛查出的二种疾病即先天性甲状腺功能低下症及苯丙酮尿症患儿的干预结果进行分析。方法采集出生72h后,充足哺乳6次以上的新生儿足跟血,于专用采血滤纸上滴两个直径8mm的血斑,并在室温下自然晾干。市妇保所由专职人员向各乡镇筛查点收集血片于十天内送往宁波市妇儿医院新生儿疾病筛查办公室。结果九年来我市进行新生儿疾病筛查61363例。筛查出苯丙酮尿症患儿6名,甲状腺功能低下症患儿23名。都得到了及时的早期治疗。结论我市的新生儿疾病筛查工作开展顺利,筛查率逐年提高,对筛查出的苯丙酮尿症及甲状腺功能低下症患儿进行早期治疗,体格发育无明显影响,未发现智力低下儿。 OBJECTIVE To summarize the work experience of neonatal screening in our city over the past nine years and analyze the results of interventions on two diseases that have been identified, congenital hypothyroidism and phenylketonuria. Methods Twenty-two hours after birth, adequate neonatal heel blood of more than 6 times breastfeeding was collected. Two blood spots of 8mm in diameter were collected on special filter paper and dried naturally at room temperature. City women’s health insurance by the full-time staff to the township screening sites collected blood films sent to Ningbo Women and Children Hospital in ten days Neonatal Disease Screening Office. Results In the past nine years, 61,363 newborns were screened in our city. Six children with phenylketonuria and 23 children with hypothyroidism were screened out. Have been timely and early treatment. Conclusion The screening of neonatal diseases in our city progressed smoothly and the screening rate increased year by year. There was no significant effect on the screening of patients with phenylketonuria and hypothyroidism who had physical development but no mental retardation .