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目的 :探讨肺泡蛋白沉积症的CT表现和诊断价值。方法 :4例均有完整的临床、实验室以及胸片和高分辨率CT(HRCT)检查资料 ,4例均经肺泡灌洗术 ,其中 3例经纤支镜检、1例经肺穿刺活检病理证实。对其CT表现进行回顾性分析。结果 :本病在HRCT象上呈多样化改变 :从弥散分布的较模糊的结节影到弥漫性斑片状云雾状肺实变阴影与磨玻璃影 ,呈地图样分布 ;多见蜂窝状、网状间质性表现 ,同时伴有病变范围内光滑的小叶间隔增厚。结论 :临床表现、实验室检查、影象学检查特别是HRCT表现相结合并综合分析 ,可明确诊断 ,并不一定完全依赖于纤支镜或肺穿刺活检来确诊。
Objective: To investigate the CT findings and diagnostic value of pulmonary alveolar proteinosis. Methods: All the 4 cases had complete clinical, laboratory and chest X-ray and high resolution CT (HRCT) examination data. All of the 4 cases were treated by alveolar lavage. Three cases were examined by fiberoptic bronchoscopy and one case by lung biopsy Pathology confirmed. Their CT findings were retrospectively analyzed. Results: The disease showed a variety of changes in the HRCT images: from the more diffuse distribution of nodular shadow to diffuse patchy clouds of solidified shadow and ground glass shadow, showing a map-like distribution; more common honeycomb, Reticular interstitial manifestations, accompanied by smooth thickening of interlobular septa. Conclusion: The clinical manifestations, laboratory tests, imaging examinations combined with HRCT performance combined with comprehensive analysis can confirm the diagnosis, not necessarily depend entirely on the bronchoscopy or lung biopsy to confirm.