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应用回顾性队列研究方法，对长期接触激光的１４５名作业者和教师对照５３人的健康状况作了流行病学调查。接触者主要接触ＣＯ２等激光，每日接触６～８小时。调查显示：激光接触组神经系统、眼疲劳主诉症状、眼晶状体混浊率、混浊程度（按标准分级）、眼底黄斑区色素紊乱的发生率明显高于对照组，并有统计学意义。故提议：激光作业者的个人防护及定期职业性健康监护相当重要。
A retrospective cohort study was conducted to investigate the health status of 145 workers who had long-term exposure to laser and 53 teachers who were teachers. The main contact with CO2 laser exposure, daily contact with 6 to 8 hours. The investigation showed that the incidences of macular degeneration and macular degeneration were significantly higher in the laser-exposed group than those in the control group, mainly in the nervous system of the laser exposure group, symptoms of ocular fatigue, opacity and turbidity of the ophthalmic lens. It is therefore proposed that personal protection and regular occupational health monitoring of laser operators are of considerable importance.