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大多数研究表明,用E花环检测T细胞数,随年轻人到老年人组而减低,体外对PHA和同种异体细胞反应也如此。但在衰老过程中表面带有免疫球蛋白的B细胞以及具有Fc(EA)受体和C_3b(EAC)受体的细胞数量相对恒定。而见于非T和T细胞两群中的自然杀伤(NK)细胞——Fc受体阳
Most studies show that the number of T cells detected by the E-rosette decreases with younger age groups and so does the PHA and allogeneic cell response in vitro. However, the number of B cells with immunoglobulin on the surface and the cells with Fc (EA) receptor and C_3b (EAC) receptor during aging are relatively constant. Whereas the natural killer (NK) cells found in two non-T and T-cell populations - Fc receptor tyrosine