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为了降低复方制剂的生产成本，研究了克拉维酸（CA）与阿莫西林（Amox）不同配比之复方制剂的体外抑酶率。发现当CA与Amox的比率由1变化到1／10时，其抑酶率降低较少；而当该比率由1／10变化到1／50时，抑酶率则显著降低。建议开发较低CA含量的制剂。
In order to reduce the production cost of compound preparation, the inhibitory rates of in vitro inhibition of compound preparations with different ratios of clavulanic acid (CA) and amoxicillin (Amox) were studied. It was found that when the ratio of CA to Amox changed from 1 to 1/10, the inhibition rate decreased less. When the ratio changed from 1/10 to 1/50, the inhibition rate decreased significantly. It is recommended to develop formulations with lower CA content.