细菌感染性疾病是淡水养殖业的常见疾病,一般多采用抗菌药物防治此类疾病[1]。养殖业抗菌药物的不恰当使用,使得许多软体动物来源的致病嗜水气单胞菌产生了耐药性。细菌耐药性可以通过多种方式在同一种属乃至不同种属细菌之间转移扩散,造成耐药菌株大量出现,严重威胁人类用药安 Bacterial infectious diseases are common diseases in freshwater aquaculture. Antibiotic drugs are generally used to prevent and treat such diseases [1]. Inappropriate use of aquaculture antimicrobials has led to the development of resistance to many mollusk-derived pathogenic Aeromonas hydrophila strains. Bacterial drug resistance can be transferred in a variety of ways in the same species or even between different species of bacteria spread, resulting in a large number of resistant strains, a serious threat to human medication safety