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新的抗真菌制剂在咪唑领域中新的抗真菌制剂Oxicona-zole(1)对许多临床重要真菌有活性,对豚鼠的毛发癣菌病和小鼠阴道念珠菌病都具有局部活性。咪唑衍生物(2)和(3)与克霉唑(Clotri-mazole)的结构近似。(2)对白色念珠菌和星状
New antifungal preparations Oxicona-zole (1), a new antifungal agent in the field of imidazole, is active against many clinically important fungi and has local activity against trichophytosis and mouse vaginal candidiasis in guinea pigs. The structures of imidazole derivatives (2) and (3) are similar to that of Clotri-mazole. (2) Candida albicans and star-shaped