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目的探讨液基细胞学检测(thinprep cytoiogy test,TCT)技术在妇科门诊宫颈癌筛查中的应用价值。方法对1 247例年龄18～50岁妇女宫颈细胞进行TCT,对各年龄组的结果分析对比。结果 1 247例TCT中,正常、炎症者1 154例,占92.5%;TCT阳性者93例,占7.5%,其中未明确意义的鳞状不典型鳞状上皮细胞(ASCUS)与不除外高度鳞状上皮内病变的不典型细胞(ASC-H)者78例,占6.3%;低度鳞状上皮内病变(L SIL)者11例,占0.9%;高度上皮内病变(HSIL)者4例,占0.3%;未发现鳞状细胞癌(SCC)。各年龄组TCT阳性者检出率经统计学处理表明,只有30岁～组ASCUS与ASC-H的检出率明显高于20岁～组,差异有统计学意义(P<0.05)。结论TCT细胞学检查在早期筛查宫颈癌及癌前病变有一定的临床价值。
Objective To investigate the value of TCT in the screening of cervical cancer in gynecology clinic. Methods Totally 1 247 women aged 18-50 years old were treated with TCT, and the results of each age group were analyzed and compared. Results 1 247 cases of TCT, 1 154 cases of normal inflammation, accounting for 92.5%; 93 cases of TCT positive, accounting for 7.5%, of which the unspecified squamous atypical squamous cells (ASCUS) and not excluding the height scale There were 78 cases (ASC-H) of ASC-H, accounting for 6.3%; 11 cases of low grade squamous intraepithelial lesion (L SIL), accounting for 0.9%; 4 cases of high intraepithelial lesion (HSIL) , Accounting for 0.3%; no squamous cell carcinoma (SCC) was found. The detection rate of TCT positive in all age groups was statistically analyzed. The detection rate of ASCUS and ASC-H in the 30-year-old group was significantly higher than that in the 20-year-old group (P <0.05). Conclusion TCT cytology in early screening of cervical cancer and precancerous lesions have some clinical value.