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特比萘芬( terbinafine)属丙烯胺类抗真菌药,可特异性地阻断真菌细胞膜角鲨烯环氧化酶的活性,从而造成角鲨烯在膜内的堆积和麦角固醇的耗竭。此双重作用的结果产生了杀菌效应。但并非所有的病原真菌均对该药高度敏感,有报道除对近平滑念珠菌外,特比萘芬对其它致病念珠菌
Terbinafine is an allylamine antifungal agent that specifically blocks the activity of the fungal cell membrane squalene epoxidase, resulting in the accumulation of squalene in the membrane and the depletion of ergosterol. The dual effect of the resulting bactericidal effect. But not all of the pathogenic fungi are highly sensitive to the drug, there are reports in addition to the parapsilosis Candida, terbinafine on other pathogenic Candida