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目的探讨急性重症颅脑疾病患者心肌酶谱变化。方法急性重症颅脑疾病患者225例(观察组),同期非颅脑疾病患者90例(对照组),采用免疫抑制法检测2组入住ICU第1、2、3、4、5天肌酸激酶(creatine kinase,CK)、肌酸激酶同工酶(creatine kinase-MB,CK-MB)水平。结果观察组CK、CK-MB水平高于对照组(P<0.05),其中CK、CK-MB异常升高5例。结论急性重症颅脑疾病患者CK、CK-MB升高。
Objective To investigate the changes of myocardial enzymes in patients with acute severe craniocerebral diseases. Methods 225 cases of acute severe craniocerebral disease (observation group) and 90 cases of non-craniocerebral disease (control group) were enrolled in this study. Two groups of creatine kinase creatine kinase (CK) and creatine kinase-MB (CK-MB) levels. Results The levels of CK and CK-MB in observation group were higher than those in control group (P <0.05). CK and CK-MB were abnormally increased in 5 cases. Conclusions Patients with acute severe craniocerebral disease have elevated CK and CK-MB.