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目的讨论血液净化联合前列地尔治疗高脂血症性胰腺炎的疗效,为日后的临床治疗提供参考。方法高脂血症性胰腺炎患者160例,随机分为观察组及对照组,各80例。对照组患者给予前列地尔治疗,观察组患者在对照组的基础上,联合血液净化治疗,对比两组患者的临床疗效。结果经过临床治疗,观察组患者显效65例(81.25%),有效14例(17.50%),无效1例(1.25%),总有效率为98.75%,血淀粉酶转阴率为87.50%;对照组患者显效51例(63.75%),有效10例(12.50%),无效19例(23.75%),总有效率为76.25%,血淀粉酶阴转率为52.50%,两组患者比较差异有统计学意义(P<0.05)。结论对高脂血症性胰腺炎患者应用血液净化联合前列地尔治疗,可有效提高临床有效率,并且帮助患者在短期内实现血淀粉酶转阴,可在临床治疗中推广应用。
Objective To discuss the curative effect of blood purification combined with alprostadil in the treatment of hyperlipidemic pancreatitis and provide reference for future clinical treatment. Methods 160 cases of hyperlipidemic pancreatitis were randomly divided into observation group and control group, 80 cases each. Patients in the control group were treated with alprostadil, and patients in the observation group were treated with blood purification on the basis of the control group, and the clinical efficacy was compared between the two groups. Results After clinical treatment, 65 cases (81.25%) were markedly effective in observation group, 14 cases (17.50%) were effective, 1 case (1.25%) were ineffective, the total effective rate was 98.75%, and the conversion rate of serum amylase was 87.50% There were 51 patients (63.75%), 10 (12.50%) effective, 19 ineffective (23.75%), the total effective rate was 76.25% and the blood amylase negative conversion rate was 52.50%. There were statistically significant differences between the two groups Significance (P <0.05). Conclusion The application of blood purification combined with alprostadil in patients with hyperlipidemic pancreatitis can effectively improve the clinical efficiency and help patients to achieve the blood amylase negative in the short term, which can be widely used in clinical treatment.