心肌肥厚是血压升高和后负荷增加最初的生理适应性反应,也是许多心血管疾病,如高血压、心肌梗死、心脏瓣膜病、心肌病等共同的病理生理过程。尽管通过药物干预可将血压控制于正常范围,但心肌肥厚仍将不可避免地逐渐进展至慢性心力衰竭。事实上心肌肥厚是心血管疾病的一个独立危 Cardiac hypertrophy is the initial physiological response to elevated blood pressure and increased afterload, and is also a common pathophysiological process of many cardiovascular diseases such as hypertension, myocardial infarction, valvular heart disease, and cardiomyopathy. Although blood pressure can be controlled within the normal range by drug intervention, myocardial hypertrophy will inevitably progress to chronic heart failure. In fact, cardiac hypertrophy is an independent risk of cardiovascular disease