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目的探讨子宫内膜异位症患者血清VEGF及其受体的变化。方法选取2012年7月~2013年5月收治的41例子宫内膜异位症患者为观察组,同时期体检的41例健康妇女为对照组,将两组妇女的血清VEGF及其受体1、2水平进行比较。结果观察组的血清VEGF及其受体1、2水平均高于对照组,并且高r-AFS分期者高于低r-AFS分期者,P均<0.05,均有显著性差异。结论子宫内膜异位症患者血清VEGF及其受体均呈现较高的水平,并且越严重者水平越高。
Objective To investigate the changes of serum VEGF and its receptor in patients with endometriosis. Methods Forty-one patients with endometriosis admitted from July 2012 to May 2013 were selected as observation group and 41 healthy women undergoing physical examination as control group. Serum levels of VEGF and its receptor 1 , 2 levels are compared. Results The levels of serum VEGF and its receptor 1 and 2 in the observation group were higher than those in the control group, and were significantly higher in the high r-AFS stage than in the low r-AFS stage (all P <0.05). Conclusion Serum VEGF and its receptor in patients with endometriosis have higher levels, and the more serious the level is higher.