克山病是一种原因未明的地方性心肌病。自本病被发现迄今已逾几十年。关于克山病的病因,学者们先后提出一氧化碳中毒,病毒感染等学说。诸家之说虽各持有据,但都难以全面地解释克山病的流行病学特点。于维汉基于流行病学调查和临床防治材料,提出了营养学说,认为克山病的发病主要与病区水、土壤和粮食中某些营养物质,尤其是微量元素缺乏或失平衡 Keshan disease is an unknown cause of endemic cardiomyopathy. Since the disease was discovered so far more than a few decades. On the etiology of Keshan disease, scholars have put forward carbon monoxide poisoning, viral infection and other theories. Although all said that they hold the data, it is difficult to fully explain the epidemiological characteristics of Keshan disease. Based on the epidemiological investigation and clinical prevention and treatment materials, Yu Weihan put forward the theory of nutrition, saying that the incidence of Keshan disease is mainly related to the lack or imbalance of certain nutrients in water, soil and food in the ward, especially the trace elements