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目的:探讨急性脑梗死患者继发出血性转化(HT)的危险因素。方法:采用方便抽样方法,选取432例急性脑梗死患者,按照是否发生HT分为观察组67例和对照组365例,比较两组患者急性脑梗死继发HT情况并进行影响因素的Logistic回归分析。结果:67例(15.5%)患者发生HT,Logistic回归分析显示,空腹血糖升高(OR=1.985)、心房颤动(OR=1.904)、溶栓治疗(OR=2.110)、大面积脑梗(OR=4.836)、低LDLC(OR=2.866)为HT发生的危险因素。结论:应重视对急性脑梗死患者危险因素的控制,以降低HT发生率,改善急性脑梗死患者预后。
Objective: To explore the risk factors of secondary hemorrhagic transformation (HT) in patients with acute cerebral infarction. Methods: A total of 432 patients with acute cerebral infarction were randomly divided into observation group (67 cases) and control group (365 cases) by means of convenient sampling method. Logistic regression analysis was performed to compare the two groups of patients with secondary HT after acute cerebral infarction . Results: Sixty-five patients (15.5%) had HT and logistic regression analysis showed that fasting blood glucose (OR = 1.985), atrial fibrillation (OR = 1.904), thrombolysis (OR = 2.110) = 4.836), low LDLC (OR = 2.866) is a risk factor for HT. Conclusion: The risk factors of patients with acute cerebral infarction should be emphasized in order to reduce the incidence of HT and improve the prognosis of patients with acute cerebral infarction.