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急性有机磷农药中毒(AOPP)致呼吸肌麻痹(RMP)是中间综合征(IMS)症侯群中病死率极高的危象,迄今尚无肯定的有效治疗方法。寻找合理有效的治疗方案,显得十分重要。1998年1月以来,我们在综合治疗的基础上加用血液灌流(HP)措施,治疗13例IMS,其中包括9例RMP患者,结果满意,报告如下。1 资料与方法1.1 临床资料本文入选的病例均系1995年1月至2000年6月收住院治疗的中、重度AOPP患者,共312例。1998年1月以后的150例中发生IMS13例(8.67%),其中RMP9例,除9例RMP患者及时给予机械通气外,13例IMS患者均加用HP治疗措施(治疗组)。1997年12月以前的162例中发生IMS12例(7.41%).其中RMP8例,RMP患者常规予以机械通气治疗(对照组)。两组男女之比分别为1:1.17和1:1.40,平均年龄为28.5岁和29.1岁;两组患者均为经消化道吸收中毒,平均口
Acute Organophosphorus Pesticide Poisoning (AOPP) Respiratory muscle paralysis (RMP) is a very high mortality risk among the syndromes of intermediate syndrome (IMS), so far there is no definitive and effective treatment. Looking for a reasonable and effective treatment program, it is very important. Since January 1998, we have applied hemoperfusion (HP) measures to treat 13 patients with IMS, including 9 patients with RMP, on the basis of comprehensive treatment. The results are satisfactory and the report is as follows. 1 Materials and Methods 1.1 Clinical data The selected cases were from January 1995 to June 2000 admitted to hospital for treatment of moderate and severe AOPP patients, a total of 312 cases. IMS1 occurred in 13 cases (8.67%) after January 1998 and in 9 cases of RMP, 9 cases of RMP and 9 cases of RMP were given mechanical ventilation. 13 IMS patients were treated with HP (treatment group). IMS12 occurred in 162 cases (7.41%) before December 1997. Among them, 8 cases of RMP and RMP were routinely treated with mechanical ventilation (control group). The ratio of male to female in the two groups was 1: 1.17 and 1: 1.40, respectively, with the average age of 28.5 years and 29.1 years. The two groups of patients were all absorbed by the digestive tract with an average mouth