右美托咪啶为新型高选择性α2肾上腺素能受体激动剂,具有镇静、镇痛、抑制交感神经活性和无呼吸抑制等特点,不良反应少而轻。右美托咪啶可稳定围手术期血流动力学、减少麻醉药物用量,也在重症监护病房患者的镇静、非气管插管患者的手术和操作中得到广泛应用。近年来,该药在抗寒战、防治心肌缺血、抗心律失常诸多临床实践中获得成功应用。 Dexmedetomidine is a new and highly selective α2 adrenergic receptor agonist with the characteristics of sedation, analgesia, inhibition of sympathetic activity and non-respiratory depression, with less and less adverse reactions. Dexmedetomidine stabilizes perioperative hemodynamics and reduces the amount of anesthetic used. It is also widely used in the sedation and non-tracheal intubation surgery and operation of patients in intensive care unit. In recent years, the medicine has been successfully applied in many anti-chills, prevention and treatment of myocardial ischemia, anti-arrhythmic clinical practice.