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随着化疗药物的广泛使用,肿瘤多药耐药(MDR)成为影响肿瘤化疗疗效和患者生存率的主要因素之一,其中P-糖蛋白介导的多药耐药成为目前研究的热点之一。本文就目前国内外在这方面的研究现状和进展作一简要综述。
With the widespread use of chemotherapeutic drugs, multidrug resistance (MDR) has become one of the main factors that affect the efficacy of chemotherapy and the survival rate of patients. Among them, P-glycoprotein-mediated multidrug resistance has become one of the hot topics . This article gives a brief overview of the research status and progress in this area at home and abroad.