在尘肺的发病机制中,矽尘引起胺代谢的破坏有重要的意义。因此,作者研究了组胺和3-(2-氨基乙基)-5-吲哚代谢的变化特点。作者在临床观察了有煤尘接触史6～20年的矿工50人。Ⅰ期矽肺392人,其中炭肺(炭末沉着病)112人,炭-硅酸盐肺156人,矽肺124人。观察对象的年龄均在40～50岁间,对照组为同年龄的男性健康人。研究指标是全血 In the pathogenesis of pneumoconiosis, the destruction of amine metabolism caused by silica dust is of great significance. Therefore, the authors studied the changing characteristics of histamine and 3- (2-aminoethyl) -5-indole metabolism. The authors have clinically observed that there are 50 miners who have had contact with coal dust for 6 to 20 years. Stage I silicosis 392 people, including carbon lung (carbon deposition disease) 112 people, 156 people carbon-silicate lung, silicosis 124 people. Subjects were aged 40 to 50 years old, the control group of the same age male healthy people. The research indicator is whole blood