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我院自1992～1998年,经胃镜下应用平阳霉素(Bleomycin, BLM)局部化疗治疗中晚期食管癌32例取得满意疗效,结果报告如下。 1 临床资料 1.1 一般资料 32例中晚期食管癌,男23例、女9例,年龄38～76岁,平均年龄63岁。出现吞咽困难2～4个月。按照李益农陆星华主编消化内镜学对中晚期食管癌内镜分型,本组分为:肿块型10例,四周狭窄型18例,溃疡浸润型4例。 1.2 操作方法 按常规插入胃镜,发现癌灶后经胃镜活检孔插入NM-1K小穿刺针,其前端伸出胃镜并对准癌灶,推出针头刺入肿瘤组织。将BLM2～4 mg加生理盐水10 ml
In our hospital from 1992 to 1998, 32 cases of advanced esophageal cancer were treated with endoscopic chemotherapy with Bleomycin (BLM). The results were as follows. 1 clinical data 1.1 General Information 32 cases of advanced esophageal cancer, 23 males and 9 females, aged 38 to 76 years, mean age 63 years. Dysphagia occurs 2 to 4 months. According to the classification of endoscopic esophageal cancer by endoscopic digestive endoscopy by Li Yiongong Lu Xinghua, this group consisted of 10 cases of mass type, 18 cases of peripheral stenosis, and 4 cases of ulcer infiltration. 1.2 Operation method According to the routine insertion of gastroscope, after finding the cancerous lesion, insert the small NM-1K puncture needle through the biopsy hole of the gastroscope. The front end of the NM-1K puncture needle protrudes from the endoscope and pushes the needle into the tumor tissue. Add BLM 2-4 mg with normal saline 10 ml