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目的:探讨新生儿神经行为测定在评价高压氧治疗新生儿重度窒息中的意义。方法:选取重度窒息新生儿72例,随机分为观察组和对照组各36例。对照组以新生儿重度窒息的常规治疗方案进行干预,观察组在对照组干预措施的基础上,加用高压氧治疗。两组患儿均在第2~3天、12~14天、26~28天进行新生儿神经行为测定,对比两组新生儿神经行为测定的结果,同时对比患儿第2~3天以及26~28天新生儿神经行为测定结果超过35分的比例。结果:观察组患者第2~3天的新生儿神经行为测定结果为(33.06±7.46)分,12~14天的新生儿神经行为测定结果为(37.36±5.17)分,26~28天的新生儿神经行为测定结果为(39.81±3.06)分,两组患儿第2~3天、12~14天的新生儿神经行为测定结果对比,差异均无统计学意义(P>0.05);观察组患儿26~28天的新生儿神经行为测定结果显著高于对照组(P<0.05);观察组第26~28天的新生儿神经行为测定≥35分的比例为97.22%,显著高于对照组(P<0.05)。结论:高压氧治疗有助于纠正重度窒息新生儿的缺氧状态,提高患儿的临床治疗效果。新生儿神经行为测定在新生儿重度窒息病情的判断和疗效的评估上有一定的应用价值。
Objective: To investigate the significance of neonatal neurobehavioral assessment in the evaluation of hyperbaric oxygen therapy for neonatal severe asphyxia. Methods: Seventy-two neonates with severe asphyxia were randomly divided into observation group (36 cases) and control group (36 cases). The control group was treated with routine treatment of neonatal severe asphyxia. The observation group was treated with hyperbaric oxygen on the basis of the intervention of the control group. Two groups of children were in the first 2 to 3 days, 12 to 14 days, 26 to 28 days neonatal neurobehavioral testing, compared with the results of two groups of neonatal neurobehavioral testing, at the same time compared with children 2 to 3 days and 26 ~ 28 days neonatal neurobehavioral results than the proportion of 35 points. Results: The neonatal neurobehavioral test result was (33.06 ± 7.46) points on the 2nd to 3rd days in the observation group and was (37.36 ± 5.17) points on the 12th to 14th day. The newborn on the 26th to 28th day (39.81 ± 3.06). There was no significant difference in neurobehavioral findings between the two groups on the 2nd to 3rd day and on the 12th to 14th day (P> 0.05). The observation group Neonatal neurobehavioral test results were significantly higher in neonates aged 26-28 days than those in control group (P <0.05). The neonatal neurobehavioral score of ≥35 was 97.22% in observation group from 26th to 28th day, which was significantly higher than that of control Group (P <0.05). Conclusion: Hyperbaric oxygen therapy can help to correct the hypoxic state of neonates with severe asphyxia and improve the clinical therapeutic effect in children. Neonatal neurobehavioral testing in neonatal severe asphyxia judgment and evaluation of the efficacy of a certain value.