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目的:观察血液透析联合血液滤过和血液灌流治疗尿毒症透析患者肾性骨病的临床疗效。方法:选取我院2013.07~2016.07共60例肾性骨病的患者,随机分为3组,即血液透析组(HD)、血液透析滤过组(HDF)、血液透析灌流组(HD+HP),比较3组患者的治疗效果。结果:治疗12周后,HDF组和HD+HP组在治疗后患者症状明显改善,血钙上升,血磷下降,PTH、β2微球蛋白明显降低,且无副作用。结论:血液透析并发肾性骨病患者进行血液透析联合血液滤过和血液灌流能明显改善患者临床症状,降低血磷和PTH,达到理想的效果。
Objective: To observe the clinical effect of hemodialysis combined with hemofiltration and hemoperfusion on renal osteodystrophy in patients with uremia and dialysis. Methods: Sixty patients with renal osteodystrophy from 2013.07 to 2016.07 in our hospital were randomly divided into three groups: hemodialysis group (HD), hemodiafiltration group (HDF), hemodialysis group (HD + HP) , Compare the treatment effect of 3 groups of patients. Results: After 12 weeks of treatment, the symptoms of patients in HDF group and HD + HP group were significantly improved after treatment. The serum calcium, phosphorus decreased, PTH and β2 microglobulin were significantly decreased, and no side effects were observed. Conclusion: Hemodialysis combined with hemodiafiltration and hemoperfusion in patients with hemodialysis and renal osteodystrophy can significantly improve the clinical symptoms, reduce serum phosphorus and PTH, and achieve the desired effect.