粒细胞一巨噬细胞集落刺激因子（GM－CSF）是由澳大利亚的Metcalf等发现。从80年代中期开始、人们逐渐发现该因子不仅对粒细胞有作用，而且对内皮细胞以及血小板的形成有影响。糖尿病（DM）的血管病变，主要表现为微血管内皮细胞损伤。我们旨在探讨非胰岛素依赖型糖尿病患者血 Granulocyte-macrophage colony-stimulating factor (GM-CSF) was discovered by Metcalf et al. In Australia. From the mid-1980s, people gradually discovered that this factor not only has an effect on granulocytes but also affects the formation of endothelial cells and platelets. Diabetes mellitus (DM) vascular lesions, mainly manifested as microvascular endothelial cell damage. We aimed to explore the blood of non-insulin-dependent diabetic patients