目的探讨磁共振扩散加权成像(DWI)、动脉自旋标记技术(ASL)、磁共振血管成像(MRA)联合应用在缺血性脑血管病诊断中的价值。方法对2010年3月-2012年5月经临床和影像学诊断的104例缺血性脑血管病患者,行常规MRI、液体衰减反转恢复序列、DWI及ASL、MRA序列检查,分析DWI、ASL、MRA多种技术显示病变的信号特征、面积大小及与血管关系。结果 DWI对急性及亚急性脑梗死的检出率为100%,对大、小面积梗死病灶检出率无明显差异;ASL对大、小面积的急性及亚急性脑梗死的检出率有差异,对大面积梗死检出率为100%,对小面积梗死的检出率为70%;DWI和ASL对短暂性脑缺血发作的检出率分别为0%、70%,液体衰减反转恢复序列对短暂性脑缺血发作患者大脑皮层下斑状缺血灶检出最敏感。结论 DWI和ASL均可用于急性脑梗死的早期诊断,ASL对大、小面积的急性及亚急性脑梗死的检出率有差异,DWI、ASL及MRA联合应用可准确评估缺血半暗区及侧支血管情况,在缺血性脑血管病诊断中有重要价值。 Objective To investigate the value of magnetic resonance diffusion weighted imaging (DWI), arterial spin labeling (ASL) and magnetic resonance angiography (MRA) in the diagnosis of ischemic cerebrovascular disease. Methods From March 2010 to May 2012, 104 patients with ischemic cerebrovascular disease diagnosed by clinical and radiological examinations were examined by conventional MRI, liquid attenuation reversal recovery sequence, DWI, ASL and MRA. DWI, ASL Various MRA techniques show lesion signal characteristics, size, and vascular relationships. Results The detection rate of DWI in acute and subacute cerebral infarction was 100%, no significant difference was found in the detection rate of large and small infarct size. The detection rate of acute and subacute cerebral infarction in small and large area of ​​ASL was different , The detection rate of large area infarction was 100% and the detection rate of small area infarction was 70%. The detection rates of DWI and ASL for transient ischemic attack were 0% and 70% Recovery sequence of transient ischemic attack in patients with cerebral cortex ischemic foci detected the most sensitive. Conclusions Both DWI and ASL can be used in the early diagnosis of acute cerebral infarction. The detection rate of acute and subacute cerebral infarction in large and small area of ​​ASL is different. The combined application of DWI, ASL and MRA can accurately evaluate the ischemic penumbra area and Collateral vessels, in the diagnosis of ischemic cerebrovascular disease has an important value.