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目的 :了解普乐林注射液对急性脑梗塞患者神经功能及生活质量的影响。方法 :70例急性脑梗塞患者随机分为两组 :急性期 (发病至开始治疗的时间 <2周 )组和恢复期 ( >2周 )组 ,均给予普乐林注射液 5 0 0 m g/d,静脉滴注 ,疗程 2周 ,比较治疗前后患者神经功能缺损程度及生活质量的变化。结果 :急性期和恢复期患者在治疗后 ,神经功能缺损积分明显下降 ,生活质量明显改善 ,而两组间比较无显著差异。总有效率分别为 85 .7%和 88.6%。未发现毒副作用。结论 :普乐林注射液能明显降低急性脑梗塞患者神经功能缺损程度及提高患者的生活质量 ,对急性期和恢复期患者均有可靠的疗效和安全性。
Objective: To investigate the effects of pokolin injection on neurological function and quality of life in patients with acute cerebral infarction. Methods: Seventy patients with acute cerebral infarction were randomly divided into two groups: acute phase (onset to treatment less than 2 weeks) and convalescence (> 2 weeks). All patients were given pullarin 500 mg / d, intravenous infusion, treatment for 2 weeks, comparing the degree of neurological deficits and quality of life before and after treatment changes. Results: After treatment, the score of neurological deficit in patients with acute phase and convalescent phase decreased significantly, and the quality of life improved obviously. There was no significant difference between the two groups. The total effective rates were 85.7% and 88.6% respectively. No side effects were found. Conclusion: Pullarin injection can significantly reduce the degree of neurological deficits in patients with acute cerebral infarction and improve the quality of life of patients with reliable efficacy and safety in both acute and convalescent patients.