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[目的]比较门冬胰岛素泵入及常规胰岛素皮下注射对2型糖尿病(T2DM )患者疗效及生活质量的影响.[方法]选取近2年来就诊于本科的 T2DM 患者120例,随机分为门冬胰岛素泵入(Ⅰ组)及常规胰岛素皮下注射治疗(Ⅱ组)两组,记录血糖水平、血糖达标时间及生活质量积分等指标.[结果]两组患者血糖水平及生活质量各维度积分在两种方案治疗后均显著改善( P <0.05).与Ⅱ组相比,Ⅰ组血糖达标时间及胰岛素用量明显降低( P <0.05),12周及24周后生活质量改善较为明显( P <0.05).[结论]采用门冬胰岛素持续泵入可以使患者血糖短时间达标,减低低血糖风险及胰岛素用量,提高生活质量,是治疗 T2DM 的有效方法.“,”Objective] To compare the effect of insulin aspart pump vs regular insulin subcutaneous injec‐tion on the efficacy and quality of life in patients with type 2 diabetes mellitus(T2DM ) .[Methods] Totally 120 patients with T2DM admitted to our department in recent 2 years were selected and randomly divided into insu‐lin aspart pump group(group Ⅰ ) and regular insulin subcutaneous injection group (group Ⅱ ) .Indictors such as blood glucose ,the time of blood glucose up to the target and the scores of quality of life were recorded .[Results] Blood glucose and the scores of quality of life were significantly improved after treatment in two groups( P < 0 .05) .Compared with group Ⅱ ,the time of blood glucose up to the target and insulin dose sig‐nificantly decreased( P < 0 .05) .The improvement of quality of life after 12 and 24 weeks was more obvious( P < 0 .05) .[Conclusion] Continuous insulin aspart pump can reach the blood glucose target in shorter time , reduce the risk of hypoglycemia as well as insulin dosage and improve the quality of life .Therefore ,it is effec‐tive method for the treatment of T 2DM .