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目的:观察米索前列醇预防产后出血的效果。方法:选择2008年4月～2010年6月自然分娩的420例产妇随机分为2组:米索组220例在胎儿娩出后立即含服米索前列醇400μg,催产素组200例在胎儿娩出后立即臀部肌肉注射催产索20 IU,采用容积法和称重法观察两组产后2 h的出血量。结果:米索组产后2h出血量为(164.43±55.16)m l,催产素组产后2h出血量为(283.57±61.34)m l,两组比较差异有统计学意义(P<0.01)。结论:含服米索前列醇预防产后出血的效果优于肌注催产索,且安全方便。
Objective: To observe the effect of misoprostol in preventing postpartum hemorrhage. Methods: From April 2008 to June 2010, 420 women of spontaneous labor were randomly divided into 2 groups: 220 patients in the misoprost group received 400 μg of misoprostol immediately after delivery and 200 in the oxytocin group Immediately after intramuscular injection of oxytocin 20 IU volume method and weighing method were used to observe the amount of bleeding 2 h postpartum. Results: The amount of bleeding in the misoprostol group was (164.43 ± 55.16) m 2 after birth and the amount of bleeding in the oxytocin group was (283.57 ± 61.34) m 2 after 2 hours of delivery. There was significant difference between the two groups (P <0.01). Conclusion: The effect of taking misoprostol on preventing postpartum hemorrhage is better than that of intramuscular injection, and it is safe and convenient.