论文部分内容阅读
目的 :探讨支气管肺泡灌洗液 (BALF)中白介素 6(IL 6)与周围型肺癌的关系。方法 :应用ELISA双抗体夹心法检测 2 8例周围型肺癌患者BALF、血清IL 6水平及 12例肺部炎性病变患者BALF中IL 6水平。结果 :周围型肺癌患者血清、BALF中IL 6水平分别高于正常人血清及肺部炎性病变患者BALF中IL 6水平 (P分别 <0 .0 1) ,周围型肺癌患者BALF中IL 6水平明显高于其自身血清IL 6(P <0 .0 0 1)。结论 :BALF中IL 6测定对周围型肺癌诊断有一定意义
Objective: To investigate the relationship between interleukin 6 (IL 6) and peripheral lung cancer in bronchoalveolar lavage fluid (BALF). Methods: BALF and serum IL-6 level in 28 patients with peripheral lung cancer and IL-6 levels in BALF of 12 patients with pulmonary inflammatory disease were detected by ELISA double antibody sandwich method. Results: IL 6 levels in serum and BALF of patients with peripheral lung cancer were significantly higher than those of BALF in patients with normal serum and pulmonary inflammatory diseases (P <0.01, respectively). IL 6 levels in BALF in patients with peripheral lung cancer Was significantly higher than its own serum IL 6 (P <0. 0 0 1). Conclusion: The determination of IL 6 in BALF has some significance in the diagnosis of peripheral lung cancer