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骨髓增生异常综合征(MDS)是造血干细胞疾病。病理形态特点为造血系统多样性增殖异常,亦表现在外周血液细胞形态的变化。临床以不明原因贫血为主,伴或不伴有白细胞及血小板减少,骨髓造血细胞三个系统都可有质与量方面的变化。故称为“骨髓增生异常综合征(MDS)”。不少 MDS可转变为急性白血病,故亦有人称为白血病前期。
Myelodysplastic syndrome (MDS) is a hematopoietic stem cell disorder. Pathological features of abnormal proliferation of hematopoietic system diversity, also showed changes in the morphology of peripheral blood cells. Clinical anemia with unexplained mainly with or without leukopenia and thrombocytopenia, bone marrow hematopoietic cells in the three systems can have qualitative and quantitative changes. It is called “myelodysplastic syndrome (MDS).” Many MDS can be transformed into acute leukemia, it is also known as pre-leukemia.