一种硝酸甘油新剂型—Nitroderm TTs(护心贴片)

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Nitroderm TTs 系硝酸甘油的皮肤贴用药膜制剂,临床用于冠心病心绞痛的预防。并可使心电图得以改善。本品是利用药膜内带有微孔的释出膜控制贮藏层内的硝酸甘油以固定的速率渗透入皮层从而维持有效而稳定的血药水平。故本品既可避免口服药物经胃肠道分解破坏和肝脏首过效应的干扰,又可避免软膏制剂在单位时间内吸收量不定和血药浓度不稳定的缺点。由于维持时间长,特别适用于防止心绞 Nitroderm TTs Department of nitric acid glycerin skin patch medication film preparation, clinical use for the prevention of angina pectoris. And ECG can be improved. This product is the use of membrane with microporous release membrane control storage layer of nitroglycerin at a fixed rate of penetration into the cortex in order to maintain effective and stable blood levels. Therefore, this product can prevent oral drugs by the gastrointestinal tract destruction and the first pass of the liver interference, but also to avoid ointment preparations in the unit of time and the concentration of unstable absorption of blood shortcomings. Due to the maintenance of a long time, especially for preventing heart failure
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