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为了解沥青对接触者遗传效应的改变，用体外淋巴细胞培养的方法，检测了２３名沥青工和１２名正常对照外周淋巴细胞姐妹染色单体互换（ＳＣＥ）率。结果表明：沥青工ＳＣＥ率明显高于对照，差异有显著性；接触组中，吸烟和不吸烟者ＳＣＥ率无显著性差异。提示：煤焦沥青具有强烈的遗传毒理学效应。
To understand the genetic effects of asparagus on contact, the sister chromatid exchange (SCE) rates of 23 asphaltenes and 12 normal control peripheral lymphocytes were examined by in vitro lymphocyte culture. The results showed that: SCE rate of asphalt workers was significantly higher than the control, the difference was significant; contact group, smoking and non-smoker SCE rate was no significant difference. Tip: Coal tar pitch has a strong genotoxic effect.