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目的:了解某院抗感染药临床使用情况,探讨其合理性。方法:以抗感染药的消耗金额、用药频次(DDDs)、日治疗费用(DDC)对某三甲医院2006年抗感染药进行归类统计、综合分析。结果:抗感染药中头孢菌素类、青霉素类、喹诺酮类、大环内酯类、林可酰胺类金额排序依次占前五位,β-内酰胺类、克林霉素、左氧氟沙星、阿奇霉素位序靠前。用药频度前20位中大多数是价格低廉的一线抗感染药物。随着抗感染药的广泛应用,细菌的耐药率也迅速增长。结论:临床抗感染药的应用情况基本合理,仍需加强抗感染药的规范应用,控制细菌耐药率的迅速增长。
Objective: To understand the clinical use of anti-infectives in a hospital and to explore its rationality. Methods: The anti-infectives in a top-three hospital were classified and analyzed with DDDs, anti-infectives consumption, DDDs and DDC. Results: The quantities of cephalosporins, penicillins, quinolones, macrolides and lincosamides in the anti-infectives ranked the top five, β-lactams, clindamycin, levofloxacin, azithromycin Order by the front. Most of the top 20 medications are cheap first-line anti-infectives. With the widespread use of anti-infectives, bacterial resistance rates have also increased rapidly. Conclusion: The clinical application of anti-infectives is basically reasonable, and the normative application of anti-infectives needs to be strengthened to control the rapid growth of bacterial resistance.