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目的:评价个体化治疗方案治疗糖尿病合并高血压应用价值。方法:2014年2月~2015年1月,收治的84例患者,随机分组,对照组、观察组各纳入42例,前者针对原有方案,修改明显获益较差方案,增加降压治疗方案,观察组制定个体化治疗方案,包括非药物治疗处方、个体化用药,加强监测调整用药方案,增减药物。结果:6个月后,观察组、对照组获得随访40例、38例;观察组HbA1c、SBP、DBP、FPG、PPG、TG、LDL、UA低于治疗前、对照组,HDL高于治疗前,对照组HbA1c、SBP、DBP低于治疗前,差异具有统计学意义(P<0.05);观察组未见不良反应,对照组出现1例,差异无统计学意义(P>0.05)。结论:个体化治疗方案治疗糖尿病合并高血压有助于增进治疗效果。
OBJECTIVE: To evaluate the value of individualized treatment in the treatment of diabetes mellitus with hypertension. Methods: From February 2014 to January 2015, 84 patients were randomly divided into control group and observation group. Each of the 42 patients was enrolled in the control group and the observation group. The former aimed at the original protocol and modified the program with obvious benefit and the antihypertensive treatment program , The observation group to develop individualized treatment programs, including non-drug treatment prescriptions, individualized medication, monitoring program to strengthen the regulation, increase and decrease of drugs. Results: After 6 months, the observation group and the control group were followed up 40 cases and 38 cases. The HbA1c, SBP, DBP, FPG, PPG, TG, LDL and UA in observation group and control group were lower than those before treatment and control group , While the control group had lower HbA1c, SBP and DBP than those before treatment (P <0.05). There was no adverse reaction in the observation group and 1 case in the control group, with no significant difference (P> 0.05). Conclusion: Individualized treatment regimens for the treatment of diabetes complicated with hypertension help to improve the therapeutic effect.