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目的分析Ⅰ期、部分Ⅱ期乳腺癌患者行保乳手术的临床效果及可行性研究。方法回顾性分析该院及自治区肿瘤医院2006年1月—2011年1月收治的86例Ⅰ期、Ⅱ期(仅T2N0M0)乳腺癌行保乳手术患者(保乳组)、选择同期住院的91例Ⅰ期、Ⅱ期(仅T2N0M0)乳腺癌行改良根治术患者(改良组),比较两组切口长度、术中出血量、手术时间、术后住院天数、术后并发症、美容效果、生存质量、远期复发及转移率。结果就各种观察指标来说:保乳组切口长度、术中出血量等明显优于改良组差异有统计学意义(P<0.05);远期复发及转移率,差异无统计学意义(P>0.05)。结论对于Ⅰ期、部分Ⅱ期乳腺癌患者实施保乳手术,具有一定可行性,可提高患者生活质量,值得推广。
Objective To analyze the clinical efficacy and feasibility of breast conserving surgery in stage Ⅰ and some stage Ⅱ breast cancer patients. Methods A total of 86 patients with stage Ⅰ and Ⅱ breast cancer (T2N0M0 breast cancer) undergoing breast-conserving surgery admitted to our hospital from January 2006 to January 2011 were retrospectively analyzed. The patients in stage Ⅰ and Ⅱ (T2N0M0) breast cancer were treated with modified radical mastectomy (modified group). The incision length, intraoperative blood loss, operation time, hospital stay, postoperative complications, cosmetic effect and survival were compared Quality, long-term recurrence and metastasis rate. Results For various observation indexes, the length of incision and blood loss in breast-conserving group were significantly better than those in the improved group (P <0.05), and the recurrence and metastasis rates in the long-term were not statistically significant (P > 0.05). Conclusion It is feasible to improve the quality of life of patients with stage Ⅰ and partial stage Ⅱ breast cancer and is worth popularizing.