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目的 :观察天红通脉口服液对实验性缺血性中风的治疗作用。方法 :通过插线法制作大鼠局灶性脑缺血模型 ,观察天红通脉口服液对模型动物的存活率、行为体征、体重增长、脑梗死面积和脑指数的影响。结果 :天红通脉口服液能提高模型大鼠的存活率 ,改善模型动物行为体征的异常 ,减少小脑缺血面积 ,降低脑缺血大鼠脑指数。结论 :天红通脉口服液对永久性局灶性脑缺血大鼠有良好的治疗作用。
Objective: To observe the therapeutic effect of Tianhong Tongmai Oral Liquid on experimental ischemic stroke. METHODS: Rat focal cerebral ischemia model was established by wire-pulling method. The effects of Tianhong Tongmai Oral Liquid on the survival rate, behavioral signs, body weight gain, cerebral infarct size and brain index of model animals were observed. Results: Tianhong Tongmai Oral Liquid could increase the survival rate of model rats, improve the abnormal behavior and signs of model animals, reduce the area of cerebellar ischemia, and decrease the cerebral index of cerebral ischemia rats. Conclusion: Tianhong Tongmai Oral Liquid has a good therapeutic effect on rats with permanent focal cerebral ischemia.