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目的:探讨重症监护病房(Intensive Care Unit,简称ICU)感染性休克患者动脉压(Pulse pressure,简称PP)的变化对预后的影响。方法:选取2015年4月—2016年4月期间医院ICU收治的感染性休克患者63例,依照治疗结局将其分为生存组(40例)与观察组(23例),比较两组患者治疗期间的PP和急性生理学及慢性健康状况评分系统(Acute physiology and chronic health evaluation scoring system,APACHEⅢ)评分值的差异。结果:生存组患者的PP值明显高于观察组(P<0.05),治疗后12 h,生存组患者的APACHEⅢ评分值明显低于观察组;治疗开始时,两组患者的PP值经组间比较其差异无统计学意义(P>0.05);治疗后6 h,生存组患者的PP值大于治疗开始时,治疗后24 h,生存组患者的PP值大于治疗后6 h;治疗后6 h,观察组患者的PP值小于治疗开始时;治疗后24 h,观察组患者的PP值小于治疗后6 h;治疗后6 h、24 h,生存组患者的PP值均明显大于观察组(P<0.05);治疗后6 h,观察组患者的PP值小于治疗开始时,患者的APACHEⅢ评分值大于治疗开始时,治疗后24 h,观察组患者的PP值小于治疗后6 h,患者的APACHEⅢ评分值大于治疗后6 h,提示观察组患者的PP与APACHEⅢ评分值之间为负相关关系。结论:PP与ICU感染性休克患者的预后有较紧密的相关性,可用于准确地判断患者的预后情况,其检测过程较为简单方便,检测结果的准确性较高。
Objective: To investigate the effect of changes of arterial pressure (PP) on the prognosis in patients with intensive care unit (ICU) septic shock. Methods: Sixty-three septic shock patients admitted to the hospital ICU from April 2015 to April 2016 were selected and divided into survival group (40 cases) and observation group (23 cases) according to the treatment outcome. The patients in two groups were compared During the period of the PP and acute physiology and chronic health evaluation scoring system (Acute physiology and chronic health evaluation scoring system, APACHE Ⅲ) scores. Results: The PP value in survival group was significantly higher than that in observation group (P <0.05). At 12 h after treatment, APACHE III score in survival group was significantly lower than that in observation group. At the beginning of treatment, (P> 0.05). At 6 h after treatment, the PP value in survival group was greater than that at the beginning of treatment. The PP value in survival group was higher than that after treatment for 24 h and 24 h after treatment. After treatment for 6 h , PP in the observation group was less than that at the beginning of treatment; PP in the observation group was less than that in the observation group at 24 h after treatment; PP values in the survival group were significantly higher than those in the observation group at 6 h and 24 h <0.05). At 6 hours after treatment, PP in observation group was lower than that at the beginning of treatment, APACHE III score was higher in treatment group than in treatment group. After treatment for 24 h, PP in observation group was less than that in 6 h after treatment. APACHE Ⅲ Score greater than 6 h after treatment, suggesting that the observation group of patients with PP and APACHE III score was negatively correlated. Conclusion: The prognosis of PP and ICU patients with septic shock is more closely related, can be used to accurately determine the prognosis of patients, the detection process is simple and convenient, the accuracy of the test results higher.