论文部分内容阅读
1951年Dameshek首先提出骨髓增殖性疾病(myeloproliferative disorders,MPD)是一类骨髓中一系或多系细胞过度增殖,导致外周血中一种或多种血细胞过度增生,但细胞形态及功能相对正常的一类造血干/祖细胞的恶性克隆性疾病。这一概念在2001年得到了扩充,WHO专家组将慢性中性粒细胞白血病及慢性嗜酸粒细胞白血病也归为
In 1951 Dameshek first proposed that myeloproliferative disorders (MPD) are hyperplasia of one or more cell lines in the bone marrow, resulting in hyperproliferation of one or more blood cells in the peripheral blood, but the morphology and function of the cells are relatively normal A class of malignant clonal diseases of hematopoietic stem / progenitor cells. This concept was expanded in 2001 and the WHO expert group also classified chronic myelogenous leukemia and chronic eosinophilic leukemia as